Endocrine Abstracts

Introduction: Some metabolic diseases, including type 1 (T1DM) and type 2 (T2DM) diabetes mellitus have an influence on bone homeostasis. These facts are of great socio-medical impact, since currently the DM2 and osteoporosis are considered public health problems.Objectives: (1) Determine the relationship between markers of bone metabolism and insulin resistance in postmenopausal women with and without T2DM.(2) Compare the bone min...

Introduction: Gender identity disorder (GID) is a disagreement between biological sexual differentiation and self-declared gender identity. The aetiology of GID remains unclear, although endocrinological, neuroanatomical and psychosocial factors are all thought to be causally involved. Polycystic ovary syndrome (PCOS) is characterized by chronic anovulation, polycystic ovarian morphology, and biochemical and/or biological signs of hyperandrogenism. Most women with PCOS also ex...

Background: Exogenous hyperthyroidism is a rare cause of thyrotoxicosis. It is caused by ingestion of excessive amounts of thyroid hormone, which could be intentional or surreptitious (known as factitious thyrotoxicosis). One of the most exceptional cause is the intake of meat or sausage containing thyroid tissue, inadvertently mixed with traces of muscles and other tissues of the animal’s neck (hamburger thyrotoxicosis). The clinical symptoms are indistinguishable from o...

Introduction: Mechanism underlying glucose-mediated development and progression of diabetic complication are incompletely understood. Atrial natriuretic peptide (ANP) is a hormone released by atrial myocytes in response to acute and chronic extracellular volume expansion. Moderate hyperglycaemia (>400 mg/dl) in diabetic rats is associated with an elevation in circulating ANP levels and in GFR (glomerular filtration rate), (1) and play a role in the development of microalbu...

Introduction: Reference ranges for classifying a patient as hyper-, normo- and hypothyroidism vary from one laboratory to another, because the techniques used, regional factors (race, iodine..), but there is also the variables of age and sex of the patient are not taken. Article Thyroid Volume 21, Number 1, 2011, 5–11 Boucai et al, published equations to adjust the normal range in terms of these variables. Evaluate these equations and see if there are significant changes ...

Introduction: The transsexuals are persons that having born with a biological sex feel to belong to the opposite sex. To obtain the sexual characters opposite to his (her) biological sex they need treatment with cross-sex hormones.This treatment with sexual steroids can produce changes in cardiovascular risk factors (CRF). There has been described that hyperhomocysteinemia is an independent CRF that is modifiable by cross-sex hormonal treatment (CHT) in ...